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		There are differents method, and it is a long story to tell here.
What I suggest you quickly is the following;
 
 Backup your db with rman
 Backup your apps by using copy or using tar or using storage snapshot/fileystem snapshot(if you have this technology)
 
 Also check this note -> What Is The Best Backup Strategy For E-Business Suite EBS 11i or R12? (Doc ID 1104894.1)
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